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Two-dimensional polyacrylamide gel electrophoresis database



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Protein list for BREAST_HN_HUMAN 
Human breast ductal histologically normal tissue  {Homo sapiens (Human)}
(map ID: siena2d:BREAST_HN_HUMAN)
Release: 5 / 01 June 2000



Protein list for breast_hn_human   133 identified spots / 48 protein entries

Gene Name Description Accession n° Spot ID Exp pI Exp Mw Mapping Methods Comment Topics References
- UNKNOWN PROTEIN FROM SPOT 2D-PAGE OF LIVER TISSUE (SPOT 118) (FRAGMENT) P31933
(ULAG_HUMAN)
1527
5.49
38'576
{Gm}
-
1
- UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX CORE PROTEIN I (EC 1.10.2.2) P31930
(UCR1_HUMAN)
3302
5.44
46'383
{Gm}
-
1
- MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) (GLYCOSYLATION-INHIBITING FACTOR) (GIF) P14174
(MIF_HUMAN)
3092
7.80
11'878
{Mi}
Pathological level
1
- KERATIN, TYPE II CYTOSKELETAL 8 (CYTOKERATIN 8) (K8) (CK 8) P05787
(K2C8_HUMAN)
1145
5.35
48'841
{Gm}
-
1
- Immunoglobulin light chain P99007
(IGLC_HUMAN)
3313
3312
3311
3310
3309
3308
3307
2299
2265
2228
7.86
7.80
7.89
7.53
7.50
7.53
7.04
6.39
6.92
6.39
24'993
25'374
25'649
24'301
24'939
25'594
25'484
24'993
24'886
25'705
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
-
-
-
-
-
-
1
1
1
1
1
1
1
1
1
1
- Immunoglobulin heavy chain gamma P99006
(IGHG_HUMAN)
422
417
395
394
393
392
389
3301
3300
3299
3298
3297
3296
3295
3294
3285
3284
1076
1075
1073
7.43
7.54
8.50
8.36
8.09
7.85
8.17
6.94
6.85
6.76
6.81
6.72
6.64
6.64
6.68
7.68
7.54
7.92
7.84
7.42
85'626
84'918
86'819
85'389
84'918
85'863
84'918
49'241
49'779
50'050
49'375
49'107
49'107
50'323
49'644
87'060
88'029
49'375
48'974
48'974
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
- HEMOGLOBIN ALPHA CHAIN P01922
(HBA_HUMAN)
3047
2978
8.15
8.90
12'457
12'691
{Gm}
{Gm}
-
-
1
1
- ES1 PROTEIN HOMOLOG (PROTEIN KNP-I) (GT335) P30042
(ES1_HUMAN)
2351
6.90
23'834
{Gm}
-
1
- ENOYL-COA HYDRATASE, MITOCHONDRIAL (EC 4.2.1.17) (SHORT CHAIN ENOYL-COA HYDRATASE) (SCEH) (ENOYL-COA HYDRATASE 1) P30084
(ECHM_HUMAN)
2221
2214
5.55
5.88
26'040
26'040
{Gm}
{Gm}
-
-
1
1
- ENDOPLASMIC RETICULUM PROTEIN ERP29 (ERP31) (ERP28) P30040
(ER29_HUMAN)
2166
5.64
26'724
{Gm}
-
1
- 3-HYDROXYISOBUTYRATE DEHYDROGENASE (EC 1.1.1.31) (HIBADH) (FRAGMENT) P31937
(D3HI_HUMAN)
2017
5.53
29'197
{Gm}
-
1
- 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] (EC 1.1.1.141) (PGDH) P15428
(PGDH_HUMAN)
2251
5.58
25'594
{Gm}
-
1
- Immunoglobulin heavy chain gamma P99006
(IGHG_HUMAN)
402
7.97
84'918
{Gm}
-
2
FGA Fibrinogen alpha chain P02671
(FIBA_HUMAN)
772
742
737
3290
3288
3287
7.00
7.11
6.85
6.87
6.95
6.78
62'158
64'099
64'458
62'332
64'278
62'506
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
-
-
1
1
1
1
1
1
Name=ALB Serum albumin P02768
(ALBU_HUMAN)
727
716
696
688
677
668
3317
5.98
5.53
5.88
5.47
5.67
5.63
5.80
66'676
67'259
66'676
67'088
66'676
66'471
66'471
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
-
-
-
1
1
1
1
1
1
1
Name=ALDOA Fructose-bisphosphate aldolase A P04075
(ALDOA_HUMAN)
1518
1506
7.94
7.74
37'916
38'080
{Mi}
{Mi}
Pathological level
Pathological level
1
1
Name=APOA1 Apolipoprotein A-I (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)] P02647
(APOA1_HUMAN)
2341
2336
5.12
5.21
23'989
23'937
{Gm}
{Gm}
-
-
1
1
Name=CALR Calreticulin [Precursor] P27797
(CALR_HUMAN)
749
4.40
62'506
{Mi,Gm}
Pathological level
3, 1
Name=CMPK UMP-CMP kinase P30085
(KCY_HUMAN)
2485
5.37
21'394
{Gm}
-
1
Name=COX5A Cytochrome c oxidase subunit 5A, mitochondrial (EC 1.9.3.1) (Cytochrome c oxidase polypeptide Va) P20674
(COX5A_HUMAN)
3314
4.90
12'717
{Mi,Gm}
Pathological level
4
Name=CTSD Cathepsin D (EC 3.4.23.5) [Contains: Cathepsin D light chain; Cathepsin D heavy chain] P07339
(CATD_HUMAN)
2117
2086
5.27
5.48
28'206
28'145
{Gm}
{Gm}
-
-
1
1
Name=FGB Fibrinogen beta chain [Contains: Fibrinopeptide B] P02675
(FIBB_HUMAN)
995
985
974
6.70
6.50
6.30
53'424
53'861
54'450
{Gm}
{Gm}
{Gm}
-
-
-
1
1
1
Name=FGG Fibrinogen gamma chain P02679
(FIBG_HUMAN)
3293
1164
1156
1142
5.36
5.59
5.45
5.29
48'708
48'400
48'576
48'841
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
1
1
1
1
Name=GAPDH Glyceraldehyde-3-phosphate dehydrogenase P04406
(G3P_HUMAN)
1719
1678
8.53
8.68
34'628
34'405
{Mi,Gm}
{Mi,Gm}
Pathological level
Pathological level
1
1
Name=GSTP1 Glutathione S-transferase P P09211
(GSTP1_HUMAN)
2398
5.40
23'325
{Gm}
-
5
Name=HBB Hemoglobin subunit beta (Hemoglobin beta chain) (Beta-globin) P02023
(HBB_HUMAN)
3026
3006
6.87
7.12
12'482
12'431
{Gm}
{Gm}
-
-
1
1
Name=HP Haptoglobin [Contains: Haptoglobin alpha chain; Haptoglobin beta chain] P00738
(HPT_HUMAN)
3303
2698
2696
2688
1495
1483
1459
1396
1381
1339
5.06
5.32
6.04
5.61
5.31
5.20
5.31
5.08
4.96
4.88
42'060
16'791
16'664
17'004
39'080
40'192
39'933
40'541
41'426
42'868
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
-
-
-
-
-
-
1
1
1
1
1
1
1
1
1
1
Name=HPX Hemopexin (Beta-1B-glycoprotein) P02790
(HEMO_HUMAN)
676
660
636
625
5.61
5.49
5.37
5.34
69'185
69'827
71'348
72'232
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
1
1
1
1
Name=HSPA5 78 kDa glucose-regulated protein [Precursor] P11021
(GRP78_HUMAN)
619
618
5.01
4.99
73'127
73'578
{Mi}
{Mi}
Pathological level
Pathological level
3, 1
3, 1
Name=HSPA9B Stress-70 protein, mitochondrial [Precursor] P38646
(GRP75_HUMAN)
703
684
5.26
5.29
68'128
67'919
{Gm}
{Gm}
Pathological level
Pathological level
3, 1
3, 1
Name=HSPD1 60 kDa heat shock protein, mitochondrial [Precursor] P10809
(CH60_HUMAN)
873
867
5.19
5.23
58'124
58'124
{Mi,Gm}
{Mi,Gm}
Pathological level
Pathological level
3, 1
3, 1
Name=LRG1 Leucine-rich alpha-2-glycoprotein (LRG) P02750
(A2GL_HUMAN)
1251
1215
1174
4.60
4.54
4.45
46'131
47'402
48'974
{Gm}
{Gm}
{Gm}
-
-
-
1
1
1
Name=PDIA3 Protein disulfide-isomerase A3 [Precursor] P30101
(PDIA3_HUMAN)
1002
1000
5.65
5.54
54'008
54'008
{Gm}
{Gm}
-
-
1
1
Name=PEBP1 Phosphatidylethanolamine-binding protein 1 P30086
(PEBP1_HUMAN)
2536
7.49
19'883
{Gm}
-
1
Name=PPIA Peptidyl-prolyl cis-trans isomerase A P05092
(PPIA_HUMAN)
2862
2842
2841
6.66
7.60
7.17
14'458
14'488
14'488
{Mi,Gm}
{Mi,Gm}
{Mi,Gm}
Pathological level
Pathological level
Pathological level
1
1
1
Name=PRDX3 Thioredoxin-dependent peroxide reductase, mitochondrial [Precursor] P30048
(PRDX3_HUMAN)
2396
6.03
23'325
{Gm}
-
1
Name=PRDX6 Peroxiredoxin-6 P30041
(PRDX6_HUMAN)
2252
6.28
25'374
{Gm}
-
1
Name=RPS27A Ubiquitin P02248
(UBIQ_HUMAN)
3267
6.90
8'818
{Gm}
-
1
Name=SERPINA1 Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1- antiproteinase) P01009
(A1AT_HUMAN)
959
952
949
924
899
5.09
5.04
4.99
4.94
4.91
55'345
55'345
55'950
56'715
58'614
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
-
1
1
1
1
1
Name=SERPINH1 Serpin H1 [Precursor] P50454
(SERPH_HUMAN)
1221
9.12
45'262
{Mi}
Pathological level
3, 1
Name=SOD1 Superoxide dismutase [Cu-Zn] P00441
(SODC_HUMAN)
2894
2749
2740
5.55
5.67
5.41
14'016
15'884
16'086
{Gm}
{Gm}
{Gm}
-
-
-
1
1
1
Name=SOD2 Superoxide dismutase [Mn], mitochondrial [Precursor] P04179
(SODM_HUMAN)
2490
2486
6.77
6.95
21'071
21'071
{Gm}
{Gm}
-
-
1
1
Name=TF Serotransferrin (Transferrin) (Siderophilin) (Beta-1-metal- binding globulin) P02787
(TRFE_HUMAN)
581
570
563
562
554
3286
3189
6.56
6.48
6.40
6.34
6.28
6.24
5.74
75'389
74'950
75'389
75'598
76'229
76'652
10'141
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
{Gm}
-
-
-
-
-
-
-
1
1
1
1
1
1
1
Name=TPI1 Triosephosphate isomerase P00938
(TPIS_HUMAN)
2279
2270
6.52
6.79
24'993
25'101
{Gm}
{Gm}
-
-
1
1
Name=TPT1 Translationally-controlled tumor protein P13693
(TCTP_HUMAN)
2471
4.87
21'788
{Gm}
-
1
Name=TUBB2C Tubulin beta-2C chain (Tubulin beta-2 chain) P05217
(TBB2C_HUMAN)
1891
4.97
51'991
{Mi}
-
1
Name=TXN Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) P10599
(THIO_HUMAN)
3061
4.89
12'354
{Mi,Gm}
Pathological level
4, 1
TRA1 ENDOPLASMIN PRECURSOR (94 KD GLUCOSE-REGULATED PROTEIN) (GRP94) (GP96 HOMOLOG) (TUMOR REJECTION ANTIGEN 1) P14625
(ENPL_HUMAN)
359
4.88
90'650
{Mi}
Pathological level
5
Mapping legends: { ARRAY(0xd9d2590) } => '', { ARRAY(0xd9d3040) } => '', { ARRAY(0xd9d3070) } => ''



Cited references

# PubMed/Medline Authors Location
[1] 9504817 BINI L., MAGI B., MARZOCCHI B., ARCURI F., TRIPODI S., CINTORINO M., SANCHEZ J-C., FRUTIGER S., HUGHES G.J., PALLINI V., HOCHSTRASSER D.F., TOSI P.; ELECTROPHORESIS 18:2832-2841(1997).
[2] 9504817 BINI L., MAGI B., MARZOCCHI B., ARCURI F., TRIPODI S., CINTORIN0 M., SANCHEZ J-C., FRUTIGER S., HUGHES G.J., PALLINI V., HOCHSTRASSER D.F., TOSI P.; ELECTROPHORESIS 18:2832-2841(1997).
[3] 12707924 Boraldi F., Bini L., Liberatori S., Armini A., Pallini V., Tiozzo R., Pasquali Ronchetti I., Quaglino D.; Electrophoresis 24:1292-1310(2003).
[4] 12373774 Magi B., Bini L., Perari M.G., Fossi A., Sanchez J.C., Hochstrasser D., Paesano S., Raggiaschi R., Santucci A., Pallini V., Rottoli P.; Electrophoresis 23:3434-3444(2005).
[5] 9504817 BINI L., MAGI B., MARZOCCHI B., ARCURI F., TRIPODI S., CINTORINO M., SANCHEZ J-C., FRUTIGER S., HUGHES G.J., PALLINI V., HOCHSTRASSER D.F., TOSI P.; ELECTROPHORESIS 18:2832-2841(1997).


Gel experimental information

Information Type Data
Map name BREAST_HN_HUMAN {Human breast ductal histologically normal tissue}
Dimension 2-D
species Homo sapiens (Human) / TaxID:9606
Number of identified spots 133
Number of identified proteins 47
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This database was constructed and maintained by Luca Bini, using the Make2D-DB II package (ver. 2.50.1) from the WORLD-2DPAGE of the ExPASy web server

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